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STX12 SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro). Belongs to the syntaxin family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 5q36
Cellular Component: endosome membrane; Golgi membrane; integral component of membrane; integral to synaptic vesicle membrane; intracellular; membrane raft; phagocytic vesicle; SNARE complex; synaptic vesicle; vesicle
Molecular Function: protein binding; SNAP receptor activity; SNARE binding
Biological Process: autophagosome assembly; cholesterol efflux; intracellular protein transport; protein stabilization; vesicle docking; vesicle fusion; vesicle-mediated transport
Reference #:  G3V7P1 (UniProtKB)
Alt. Names/Synonyms: Stx12; Syntaxin 12
Gene Symbols: Stx12
Molecular weight: 31,187 Da
Basal Isoelectric point: 5.23  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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