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IFNB1 Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9p21.3
Cellular Component: extracellular region; extracellular space
Molecular Function: chloramphenicol O-acetyltransferase activity; cytokine activity; interferon-alpha/beta receptor binding
Biological Process: adaptive immune response; B cell activation involved in immune response; B cell differentiation; B cell proliferation; blood coagulation; cell surface receptor signaling pathway; defense response to bacterium; defense response to virus; humoral immune response; macrophage activation involved in immune response; natural killer cell activation; natural killer cell activation involved in immune response; negative regulation of T cell differentiation; negative regulation of viral genome replication; positive regulation of innate immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of transcription from RNA polymerase II promoter; regulation of MHC class I biosynthetic process; response to exogenous dsRNA; response to virus; T cell activation involved in immune response
Reference #:  P01574 (UniProtKB)
Alt. Names/Synonyms: Fibroblast interferon; IFB; IFF; IFN-beta; IFNB; IFNB1; Interferon beta; interferon, beta 1, fibroblast; MGC96956
Gene Symbols: IFNB1
Molecular weight: 22,294 Da
Basal Isoelectric point: 8.93  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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