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CXCL9 Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: external side of plasma membrane; extracellular region; extracellular space
Molecular Function: chemokine activity; CXCR3 chemokine receptor binding; cytokine activity; protein binding
Biological Process: cell-cell signaling; cellular defense response; chemotaxis; defense response; defense response to virus; G-protein coupled receptor signaling pathway; immune response; inflammatory response; positive regulation of cAMP metabolic process; positive regulation of leukocyte chemotaxis; positive regulation of myoblast differentiation; positive regulation of release of sequestered calcium ion into cytosol; regulation of cell proliferation; response to lipopolysaccharide; signal transduction
Reference #:  Q07325 (UniProtKB)
Alt. Names/Synonyms: C-X-C motif chemokine 9; chemokine (C-X-C motif) ligand 9; CMK; crg-10; CXCL9; Gamma-interferon-induced monokine; Humig; MIG; monokine induced by gamma interferon; SCYB9; Small-inducible cytokine B9
Gene Symbols: CXCL9
Molecular weight: 14,019 Da
Basal Isoelectric point: 10.39  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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