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KLC1 a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 6q32
Cellular Component: axon; cell soma; ciliary rootlet; cytoplasm; cytoplasmic vesicle; cytosol; growth cone; kinesin complex; membrane; microtubule; neuron projection; vesicle
Molecular Function: microtubule motor activity; protein binding; tubulin binding
Biological Process: axon cargo transport; intracellular protein transport
Reference #:  P37285 (UniProtKB)
Alt. Names/Synonyms: kinesin 2; Kinesin light chain 1; Klc; KLC 1; Klc1; Kns2
Gene Symbols: Klc1
Molecular weight: 63,745 Da
Basal Isoelectric point: 5.73  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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