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TAL2 A chromosomal aberration involving TAL2 may be a cause of some T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;9)(q34;q32) with TCRB. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Oncoprotein; Transcription regulation
Chromosomal Location of Human Ortholog: 9q31.2
Cellular Component: nucleus
Molecular Function: DNA binding; protein binding; protein dimerization activity
Biological Process: midbrain development; multicellular organism growth; post-embryonic development; regulation of transcription from RNA polymerase II promoter; thalamus development; transcription, DNA-dependent
Disease: Leukemia, Acute Lymphoblastic
Reference #:  Q16559 (UniProtKB)
Alt. Names/Synonyms: BHLHA19; Class A basic helix-loop-helix protein 19; T-cell acute lymphocytic leukemia 2; T-cell acute lymphocytic leukemia protein 2; TAL-2; TAL2
Gene Symbols: TAL2
Molecular weight: 12,291 Da
Basal Isoelectric point: 10.48  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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