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CYP4B1 Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC; Oxidoreductase
Chromosomal Location of Human Ortholog: 1p33
Cellular Component: endoplasmic reticulum membrane
Molecular Function: drug binding; fluorene oxygenase activity; heme binding; iron ion binding; oxygen binding; toxin binding
Biological Process: biphenyl metabolic process; exogenous drug catabolic process; fluorene metabolic process
Reference #:  P13584 (UniProtKB)
Alt. Names/Synonyms: CP4B1; CYP4B1; CYPIVB1; Cytochrome P450 4B1; cytochrome P450, family 4, subfamily B, polypeptide 1; cytochrome P450, subfamily IVB, polypeptide 1; Cytochrome P450-HP; microsomal monooxygenase; P-450HP
Gene Symbols: CYP4B1
Molecular weight: 58,991 Da
Basal Isoelectric point: 8.47  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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