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RAD51AP1 May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 12p13.32
Cellular Component: nuclear chromatin; nucleoplasm; nucleus; protein complex
Molecular Function: double-stranded DNA binding; protein binding; RNA binding; single-stranded DNA binding
Biological Process: DNA repair; DNA synthesis involved in DNA repair; double-strand break repair via homologous recombination; strand displacement
Reference #:  Q96B01 (UniProtKB)
Alt. Names/Synonyms: PIR51; R51A1; RAD51 associated protein 1; RAD51-associated protein 1; RAD51-interacting protein; RAD51AP1
Gene Symbols: RAD51AP1
Molecular weight: 38,457 Da
Basal Isoelectric point: 9.18  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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