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Protein Page:

ANGPT4 Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: extracellular region; extracellular space
Molecular Function: receptor tyrosine kinase binding; transmembrane receptor protein tyrosine kinase activator activity
Biological Process: endothelial cell proliferation; leukocyte migration; negative regulation of angiogenesis; negative regulation of apoptosis; negative regulation of blood vessel endothelial cell migration; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of peptidyl-tyrosine phosphorylation
Reference #:  Q9Y264 (UniProtKB)
Alt. Names/Synonyms: AGP4; ANG-3; ANG-4; ANG3; ANG4; angiopoietin 4; Angiopoietin-3; Angiopoietin-4; ANGP4; ANGPT4; dJ824F16.2 (angiopoietin 4); MGC138181; MGC138183
Gene Symbols: ANGPT4
Molecular weight: 56,849 Da
Basal Isoelectric point: 9.1  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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