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NPFFR1 Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 10q22.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; peptide binding
Biological Process: cellular response to hormone stimulus
Reference #:  Q9GZQ6 (UniProtKB)
Alt. Names/Synonyms: FLJ10751; G protein-coupled receptor 147; G-protein coupled receptor 147; GPR147; neuropeptide FF 1; Neuropeptide FF receptor 1; NPFF1; NPFF1R1; NPFFR1; OT7T022; RFamide-related peptide receptor OT7T022
Gene Symbols: NPFFR1
Molecular weight: 47,819 Da
Basal Isoelectric point: 9.54  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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