a multifunctional enzyme that possesses protein kinase and endoribonuclease activity, Mediator of interferon action, which play a role in mediating resistance to virus infection and apoptosis. Might play a central role in the regulation of mRNA turnover. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.26.-; Kinase, protein; Other group; Other-Unique family; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Ribonuclease
Molecular Function: ATP binding; endoribonuclease activity; metal ion binding; protein binding; protein kinase activity; ribonucleoprotein complex binding; RNA binding; rRNA binding
Biological Process: defense response to virus; fat cell differentiation; mRNA processing; negative regulation of viral genome replication; positive regulation of glucose import in response to insulin stimulus; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; regulation of mRNA stability; RNA phosphodiester bond hydrolysis, endonucleolytic; rRNA processing