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Protein Page:

GAK Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; EC; Kinase, protein; NAK family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: cytosol; Golgi apparatus; intracellular membrane-bound organelle; membrane; vesicle
Molecular Function: chaperone binding; cyclin binding; protein binding
Biological Process: chaperone cofactor-dependent protein folding; endoplasmic reticulum organization and biogenesis; Golgi organization and biogenesis; receptor-mediated endocytosis; synaptic vesicle uncoating
Reference #:  O14976 (UniProtKB)
Alt. Names/Synonyms: cyclin G associated kinase; Cyclin-G-associated kinase; FLJ16629; FLJ40395; GAK; MGC99654
Gene Symbols: GAK
Molecular weight: 143,191 Da
Basal Isoelectric point: 5.49  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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