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CYP2B6 cytochrome P450, subfamily IIB. Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Phosphorylation is accompanied by a decrease in enzyme activity. Note: This description may include information from UniProtKB.
Protein type: Cofactor and Vitamin Metabolism - retinol; EC; Lipid Metabolism - arachidonic acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: intracellular membrane-bound organelle
Molecular Function: arachidonic acid epoxygenase activity
Biological Process: epoxygenase P450 pathway
Reference #:  P00176 (UniProtKB)
Alt. Names/Synonyms: CP2B1; Cyp2b-1; Cyp2b1; CYP2B1; Cyp2b12; CYPIIB1; CYPIIB12; cytochrome P-450b type b; Cytochrome P450 2B1; cytochrome P450 2B12; cytochrome P450, family 2, subfamily b, polypeptide 12; Cytochrome P450-B; Cytochrome P450-LM2; Cytochrome P450-PB1; Cytochrome P450-PB2; Cytochrome P450b
Gene Symbols: Cyp2b1
Molecular weight: 55,934 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
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Protein Structure Not Found.
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