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Protein Page:

PLAGL1 Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 6q24.2
Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; nuclear body; nucleoplasm; nucleus
Molecular Function: DNA binding
Biological Process: apoptosis; cell cycle arrest; cell differentiation; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; positive regulation of transcription from RNA polymerase II promoter
Disease: Diabetes Mellitus, Transient Neonatal, 1
Reference #:  Q9UM63 (UniProtKB)
Alt. Names/Synonyms: DKFZp781P1017; Lost on transformation 1; LOT-1; LOT1; MGC126275; MGC126276; PLAG-like 1; PLAGL1; PLAL1; pleiomorphic adenoma gene-like 1; pleiomorphic adenoma gene-like protein 1; Pleiomorphic adenoma-like protein 1; Tumor supressor ZAC; ZAC; ZAC tumor supressor; ZAC1; Zinc finger protein PLAGL1
Gene Symbols: PLAGL1
Molecular weight: 50,819 Da
Basal Isoelectric point: 8.85  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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