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Protein Page:

MTPN Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 7q33
Cellular Component: cytosol; F-actin capping protein complex; nucleus
Biological Process: activation of NF-kappaB transcription factor; cell growth; positive regulation of cell growth; positive regulation of protein metabolic process
Reference #:  P58546 (UniProtKB)
Alt. Names/Synonyms: FLJ31098; FLJ99857; GCDP; granule cell differentiation protein; MTPN; Myotrophin; Protein V-1; V-1
Gene Symbols: MTPN
Molecular weight: 12,895 Da
Basal Isoelectric point: 5.27  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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