Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
Home | Login
About PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Search / Browse Functions
Protein Page:

LRPAP1 Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis. Belongs to the alpha-2-MRAP family. Note: This description may include information from UniProtKB.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: cis-Golgi network; endoplasmic reticulum; endosome; ER-Golgi intermediate compartment; extracellular region; Golgi apparatus; plasma membrane
Molecular Function: beta-amyloid binding; low-density lipoprotein receptor binding; protein binding; receptor antagonist activity; receptor binding
Biological Process: negative regulation of protein binding; regulation of receptor-mediated endocytosis; transcytosis
Disease: Myopia 23, Autosomal Recessive
Reference #:  P30533 (UniProtKB)
Alt. Names/Synonyms: A2MRAP; A2RAP; Alpha-2-macroglobulin receptor-associated protein; alpha-2-macroglobulin receptor-associated protein 1; Alpha-2-MRAP; AMRP; HBP44; lipoprotein receptor associated protein; low density lipoprotein receptor-related protein associated protein 1; Low density lipoprotein receptor-related protein-associated protein 1; low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1); LRPAP1; MGC138272; MRAP; RAP
Gene Symbols: LRPAP1
Molecular weight: 41,466 Da
Basal Isoelectric point: 8.73  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script

STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB