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TXNDC11 May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Belongs to the protein disulfide isomerase family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 16p13.13
Cellular Component: endoplasmic reticulum
Molecular Function: protein binding; protein disulfide isomerase activity
Biological Process: protein folding
Reference #:  Q6PKC3 (UniProtKB)
Alt. Names/Synonyms: EF-hand binding protein 1; EF-hand-binding protein 1; EFP1; thioredoxin domain containing 11; Thioredoxin domain-containing protein 11; TXD11; TXNDC11
Gene Symbols: TXNDC11
Molecular weight: 110,529 Da
Basal Isoelectric point: 6.11  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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