May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Homodimer. Binds LGALS3BP. Interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Interacts with laminin (via poly-N- acetyllactosamine). Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion. Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Extracellular matrix; Secreted
Molecular Function: lactose binding; laminin binding; protein binding; protein homodimerization activity; RNA binding; signal transducer activity
Biological Process: apoptosis; cellular protein metabolic process; myoblast differentiation; plasma cell differentiation; positive regulation of erythrocyte aggregation; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of virion penetration into host cell; post-translational protein modification; regulation of apoptosis; response to axon injury; response to drug; signal transduction; T cell costimulation