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AVPR1A Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 12q14.2
Cellular Component: endosome; integral to plasma membrane; plasma membrane
Molecular Function: peptide binding; protein binding; protein kinase C binding; vasopressin receptor activity
Biological Process: blood circulation; cellular response to hormone stimulus; generation of precursor metabolites and energy; maternal behavior; phospholipase C activation; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin
Reference #:  P37288 (UniProtKB)
Alt. Names/Synonyms: Antidiuretic hormone receptor 1a; arginine vasopressin receptor 1A; AVPR V1a; AVPR1; AVPR1A; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; V1a vasopressin receptor; V1aR; Vascular/hepatic-type arginine vasopressin receptor; Vasopressin V1a receptor
Gene Symbols: AVPR1A
Molecular weight: 46,800 Da
Basal Isoelectric point: 9.48  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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