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Protein Page:

TSPY1 May be involved in sperm differentiation and proliferation. TSPY is located in the gonadoblastoma critical region and is preferentially expressed in tumor germ cells of gonadoblastoma specimens. Expression also correlates with testicular seminoma and tumorigenesis of the prostate gland. Belongs to the nucleosome assembly protein (NAP) family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Yp11.2
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: cell differentiation; cell proliferation; gonadal mesoderm development; nucleosome assembly; sex differentiation; spermatogenesis
Disease: Gonadoblastoma
Reference #:  Q01534 (UniProtKB)
Alt. Names/Synonyms: Cancer/testis antigen 78; CT78; DYS14; pJA923; testis specific protein, Y-linked 1; Testis-specific Y-encoded protein 1; TSPY; TSPY1
Gene Symbols: TSPY1
Molecular weight: 35,012 Da
Basal Isoelectric point: 5.29  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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