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CD97 Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 19p13.12
Cellular Component: focal adhesion; integral component of plasma membrane; membrane; plasma membrane; secretory granule membrane
Molecular Function: calcium ion binding; G-protein coupled receptor activity; protein binding; transmembrane receptor activity
Biological Process: cell adhesion; cell motility; cell surface receptor signaling pathway; cell-cell signaling; G-protein coupled receptor signaling pathway; immune response; inflammatory response; neutrophil degranulation
Reference #:  P48960 (UniProtKB)
Alt. Names/Synonyms: CD97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; Leukocyte antigen CD97; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1
Gene Symbols: ADGRE5
Molecular weight: 91,869 Da
Basal Isoelectric point: 6.5  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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