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KCNE3 Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Belongs to the potassium channel KCNE family. Note: This description may include information from UniProtKB.
Protein type: Channel, potassium
Chromosomal Location of Human Ortholog: 11q13.4
Cellular Component: cytoplasm; dendrite; lipid raft; perikaryon; plasma membrane; vesicle; voltage-gated potassium channel complex
Molecular Function: potassium channel regulator activity; protein binding
Disease: Brugada Syndrome 6
Reference #:  Q9Y6H6 (UniProtKB)
Alt. Names/Synonyms: cardiac voltage-gated potassium channel accessory subunit; DKFZp781H21101; HOKPP; HYPP; KCNE3; MGC102685; MGC129924; minimum potassium ion channel-related peptide 2; minK-related peptide 2; MiRP2; potassium channel subunit beta MiRP2; Potassium voltage-gated channel subfamily E member; potassium voltage-gated channel subfamily E member 3; potassium voltage-gated channel, Isk-related family, member 3; voltage-gated K+ channel subunit MIRP2
Gene Symbols: KCNE3
Molecular weight: 11,710 Da
Basal Isoelectric point: 8.82  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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