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Protein Page:
LAGE3

Overview
LAGE3 a member of the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008]
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: nuclear body; nucleoplasm
Molecular Function: protein binding
Biological Process: tRNA processing
Disease: Galloway-mowat Syndrome 2, X-linked
Reference #:  Q14657 (UniProtKB)
Alt. Names/Synonyms: CVG5; DXS9879E; DXS9951E; ESO3; ITBA2; L antigen family member 3; L antigen family, member 3; LAGE3; Protein ESO-3; Protein ITBA2
Gene Symbols: LAGE3
Molecular weight: 14,804 Da
Basal Isoelectric point: 8.88  Predict pI for various phosphorylation states
Select Structure to View Below

LAGE3

Protein Structure Not Found.

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