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CPT1B a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]
Protein type: EC; Lipid Metabolism - fatty acid; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 22q13.33
Cellular Component: integral component of membrane; mitochondrial outer membrane; mitochondrion
Molecular Function: carnitine O-palmitoyltransferase activity; protein binding
Biological Process: carnitine shuttle; fatty acid beta-oxidation
Reference #:  Q92523 (UniProtKB)
Alt. Names/Synonyms: Carnitine O-palmitoyltransferase 1, muscle isoform; carnitine O-palmitoyltransferase I, mitochondrial muscle isoform; Carnitine O-palmitoyltransferase I, muscle isoform; Carnitine palmitoyltransferase 1B; carnitine palmitoyltransferase 1B (muscle); Carnitine palmitoyltransferase I-like protein; CPT I; CPT1-M; CPT1B; CPT1M; CPTI; CPTI-M; FLJ55729; FLJ58750; KIAA1670; M-CPT1; MCCPT1; MCPT1
Gene Symbols: CPT1B
Molecular weight: 87,801 Da
Basal Isoelectric point: 8.86  Predict pI for various phosphorylation states
CST Pathways:  AMPK Signaling
Select Structure to View Below


Protein Structure Not Found.

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