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K6c Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jul 2009]
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: cytosol; extracellular exosome; intermediate filament; keratin filament
Molecular Function: protein binding; structural molecule activity
Biological Process: cornification; intermediate filament cytoskeleton organization and biogenesis; keratinization
Disease: Palmoplantar Keratoderma, Nonepidermolytic, Focal Or Diffuse
Reference #:  P48668 (UniProtKB)
Alt. Names/Synonyms: CK-6C; CK-6E; Cytokeratin-6C; Cytokeratin-6E; K2C6C; K6C; K6E; keratin 6C; keratin 6E; Keratin K6h; Keratin, type II cytoskeletal 6C; Keratin-6C; KRT6C; KRT6E; MGC102925; MGC163455; MGC163457; Type-II keratin Kb12
Gene Symbols: KRT6C
Molecular weight: 60,025 Da
Basal Isoelectric point: 8.09  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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