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GABRR3 GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR3 sub-subfamily. Note: This description may include information from UniProtKB.
Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel
Chromosomal Location of Human Ortholog: 3q11.2
Cellular Component: cell junction; plasma membrane; postsynaptic membrane
Molecular Function: chloride channel activity; extracellular ligand-gated ion channel activity; GABA-A receptor activity; protein domain specific binding
Biological Process: gamma-aminobutyric acid signaling pathway; synaptic transmission
Reference #:  A8MPY1 (UniProtKB)
Alt. Names/Synonyms: DKFZp781O1955; GABA(A) receptor subunit rho-3; GABRR3; gamma-aminobutyric acid (GABA) receptor, rho 3; Gamma-aminobutyric acid receptor subunit rho-3; GBRR3
Gene Symbols: GABRR3
Molecular weight: 54,272 Da
Basal Isoelectric point: 8.33  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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