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GPV The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: extracellular space; integral component of plasma membrane; plasma membrane; proteinaceous extracellular matrix
Molecular Function: protein binding
Biological Process: axonogenesis; blood coagulation; blood coagulation, intrinsic pathway; cell adhesion; platelet activation
Reference #:  P40197 (UniProtKB)
Alt. Names/Synonyms: CD42d; Glycoprotein 5; glycoprotein V (platelet); GP5; GPV; Platelet glycoprotein V
Gene Symbols: GP5
Molecular weight: 60,959 Da
Basal Isoelectric point: 9.73  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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