a widely-expressed multi-pass membrane protein. An organic anion pump involved in cellular detoxification. Widely expressed, with particularly high levels in prostate, but is barely detectable in liver. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family
Cellular Component: basolateral plasma membrane; integral component of plasma membrane; membrane; plasma membrane; platelet dense granule membrane
Molecular Function: 15-hydroxyprostaglandin dehydrogenase (NAD+) activity; anion transmembrane-transporting ATPase activity; ATP binding; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; ATPase activity, coupled to transmembrane movement of substances
Biological Process: platelet degranulation; positive regulation of smooth muscle cell proliferation; prostaglandin secretion; response to drug; response to organic cyclic compound; response to organonitrogen compound; transmembrane transport