Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
Home | Login
About PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Search / Browse Functions
Protein Page:
CYP3A5

Overview
CYP3A5 Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cofactor and Vitamin Metabolism - retinol; EC 1.14.14.1; Lipid Metabolism - linoleic acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle
Molecular Function: monooxygenase activity; oxidoreductase activity; oxygen binding
Biological Process: alkaloid catabolic process; drug catabolic process; steroid metabolic process; xenobiotic metabolic process
Disease: Hypertension, Essential
Reference #:  P20815 (UniProtKB)
Alt. Names/Synonyms: aryl hydrocarbon hydroxylase; CP35; CP3A5; CYP3A5; CYPIIIA5; cytochrome P-450; Cytochrome P450 3A5; Cytochrome P450 HLp2; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; Cytochrome P450-PCN3; DKFZp686L16231; flavoprotein-linked monooxygenase; microsomal monooxygenase; niphedipine oxidase; P450PCN3; PCN3
Gene Symbols: CYP3A5
Molecular weight: 57,109 Da
Basal Isoelectric point: 8.86  Predict pI for various phosphorylation states
Select Structure to View Below

CYP3A5

Protein Structure Not Found.

STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene