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ALDH1A1 Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Cofactor and Vitamin Metabolism - retinol; EC; GAP; GAP, Ras; Oxidoreductase
Chromosomal Location of Human Ortholog: 9q21.13
Cellular Component: cytoplasm; cytosol
Molecular Function: aldehyde dehydrogenase (NAD) activity; androgen binding; benzaldehyde dehydrogenase (NAD+) activity; GTPase activator activity; NAD binding; retinal dehydrogenase activity
Biological Process: aldehyde metabolic process; ethanol oxidation; positive regulation of GTPase activity; retinoid metabolic process; retinol metabolic process
Reference #:  P00352 (UniProtKB)
Alt. Names/Synonyms: acetaldehyde dehydrogenase 1; AL1A1; ALDC; aldehyde dehydrogenase 1 family, member A1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase 1A1; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; aldehyde dehydrogenase, liver cytosolic; ALDH class 1; ALDH-E1; ALDH1; ALDH11; ALDH1A1; ALHDII; MGC2318; PUMB1; RALDH 1; RalDH1; Retinal dehydrogenase 1; retinaldehyde dehydrogenase 1
Gene Symbols: ALDH1A1
Molecular weight: 54,862 Da
Basal Isoelectric point: 6.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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