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NMUR2 Receptor for the neuromedin-U and neuromedin-S neuropeptides. Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component: integral component of membrane; intracellular; plasma membrane
Molecular Function: G-protein coupled receptor activity; GTP binding; intracellular calcium activated chloride channel activity; neuromedin U binding; neuromedin U receptor activity; protein binding
Biological Process: arachidonic acid secretion; calcium ion transport; calcium-dependent phospholipase A2 activation; calcium-mediated signaling; cell-cell signaling; central nervous system development; elevation of cytosolic calcium ion concentration; feeding behavior; grooming behavior; inositol phosphate-mediated signaling; neuropeptide signaling pathway; phospholipase C-activating G-protein coupled receptor signaling pathway; reduction of food intake in response to dietary excess; regulation of smooth muscle contraction; response to pain
Reference #:  Q9GZQ4 (UniProtKB)
Alt. Names/Synonyms: FM-4; FM4; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; growth hormone secretagogue receptor family, member 4; neuromedin U receptor 2; Neuromedin-U receptor 2; NMU-R2; NMU2R; NMUR2; TGR-1; TGR1
Gene Symbols: NMUR2
Molecular weight: 47,696 Da
Basal Isoelectric point: 8.96  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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