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SLC6A18 Functions as a sodium and chloride-dependent neutral amino acid transporter. Genetic variations in SLC6A18 might contribute to the disease phentotype in some individuals with iminoglycinuria or hyperglycinuria, that carry variants in SLC36A2, SLC6A19 or SLC6A20. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A18 subfamily. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 13 C1|13 40.13 cM
Cellular Component: brush border membrane; integral to plasma membrane; plasma membrane
Molecular Function: protein binding; transporter activity
Biological Process: transport
Reference #:  O88576 (UniProtKB)
Alt. Names/Synonyms: b(0)AT3; B0AT3; D630001K16Rik; S6A18; Slc6a18; sodium and chloride dependent transporter Xtrp2; Sodium- and chloride-dependent transporter XTRP2; Sodium-dependent neutral amino acid transporter B(0)AT3; solute carrier family 6 (neurotransmitter transporter), member 18; Solute carrier family 6 member 18; system B 0 neutral amino acid transporter AT3; System B(0) neutral amino acid transporter AT3; X transporter protein 2; Xt2; Xtrp2
Gene Symbols: Slc6a18
Molecular weight: 69,229 Da
Basal Isoelectric point: 6.7  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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