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HMGB3 Binds preferentially single-stranded DNA and unwinds double stranded DNA. Belongs to the HMGB family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: Xq28
Molecular Function: DNA bending activity; double-stranded DNA binding; four-way junction DNA binding; protein binding; RNA binding
Biological Process: DNA geometric change; DNA recombination; multicellular organismal development
Disease: Microphthalmia, Syndromic 13
Reference #:  O15347 (UniProtKB)
Alt. Names/Synonyms: High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; high-mobility group (nonhistone chromosomal) protein 4; high-mobility group box 3; HMG-2a; HMG-4; HMG2A; HMG4; HMGB3; MGC90319; non-histone chromosomal protein
Gene Symbols: HMGB3
Molecular weight: 22,980 Da
Basal Isoelectric point: 8.48  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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