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HMGN2 Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Belongs to the HMGN family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1p36.11
Cellular Component: cytoplasm; extracellular space; nucleus
Molecular Function: protein binding; RNA binding
Biological Process: killing of cells of another organism
Reference #:  P05204 (UniProtKB)
Alt. Names/Synonyms: High mobility group nucleosome-binding domain-containing protein 2; high mobility group protein N2; high-mobility group (nonhistone chromosomal) protein 17; high-mobility group nucleosomal binding domain 2; HMG17; HMGN2; MGC5629; MGC88718; Non-histone chromosomal protein HMG-17; nonhistone chromosomal protein HMG-17
Gene Symbols: HMGN2
Molecular weight: 9,393 Da
Basal Isoelectric point: 10  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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