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AVEN Protects against apoptosis mediated by Apaf-1. Binds Apaf-1, BCL-2 and BAD (Bcl-xl). Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Inhibitor
Chromosomal Location of Human Ortholog: 15q14
Cellular Component: intracellular; membrane
Molecular Function: protein binding
Biological Process: negative regulation of apoptosis
Reference #:  Q9NQS1 (UniProtKB)
Alt. Names/Synonyms: apoptosis, caspase activation inhibitor; AVEN; Cell death regulator Aven; PDCD12; programmed cell death 12
Gene Symbols: AVEN
Molecular weight: 38,506 Da
Basal Isoelectric point: 4.9  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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