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SLC7A11 Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 4q28.3
Cellular Component: cell surface; integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: cystine:glutamate antiporter activity; protein binding
Biological Process: amino acid transport; leukocyte migration; response to toxin
Reference #:  Q9UPY5 (UniProtKB)
Alt. Names/Synonyms: amino acid transport system xc calcium channel blocker resistance protein CCBR1; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; CCBR1; Cystine/glutamate transporter; SLC7A11; Solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; xCT
Gene Symbols: SLC7A11
Molecular weight: 55,423 Da
Basal Isoelectric point: 9.29  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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