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SLC25A5 Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. Belongs to the mitochondrial carrier family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: Xq24
Cellular Component: extracellular matrix; integral to plasma membrane; membrane; mitochondrial inner membrane; mitochondrion; nucleus
Molecular Function: adenine transmembrane transporter activity; ATP:ADP antiporter activity; protein binding; RNA binding; ubiquitin protein ligase binding
Biological Process: positive regulation of cell proliferation; regulation of insulin secretion; transport
Reference #:  P05141 (UniProtKB)
Alt. Names/Synonyms: 2F1; AAC2; Adenine nucleotide translocator 2; adenine nucleotide translocator 2 (fibroblast); adenine nucleotide translocator), member 5; ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; ADP/ATP carrier protein; ADP/ATP translocase 2; ADT2; ANT 2; ANT2; SLC25A5; solute carrier family 25 (mitochondrial carrier; Solute carrier family 25 member 5; T2; T3
Gene Symbols: SLC25A5
Molecular weight: 32,852 Da
Basal Isoelectric point: 9.71  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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