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NuaK1 a protein kinase of the CAMKL family. Phosphorylated and activated by AKT1 during glucose starvation. May activate ATM kinase under conditions of nutrient starvation. Suppresses apoptosis induced by nutrient starvation and death receptors via inhibition of caspase 8 activation. Note: This description may include information from UniProtKB.
Protein type: CAMK group; CAMKL family; EC; Kinase, protein; NuaK subfamily; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 12q23.3
Cellular Component: cytoplasm; fibrillar center; microtubule cytoskeleton; nucleoplasm; nucleus
Molecular Function: p53 binding; protein binding; protein serine/threonine kinase activity
Biological Process: protein amino acid phosphorylation; regulation of cell adhesion; regulation of cell proliferation
Reference #:  O60285 (UniProtKB)
Alt. Names/Synonyms: AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; KIAA0537; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; NUAK1
Gene Symbols: NUAK1
Molecular weight: 74,305 Da
Basal Isoelectric point: 8.97  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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