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CKS1 Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Belongs to the CKS family. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Protein kinase, regulatory subunit
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: cyclin-dependent protein kinase holoenzyme complex; nucleoplasm; SCF ubiquitin ligase complex
Molecular Function: histone binding; protein binding; protein kinase binding; ubiquitin binding
Biological Process: positive regulation of cyclin-dependent protein kinase activity; positive regulation of transcription, DNA-dependent; regulation of mitotic cell cycle
Reference #:  P61024 (UniProtKB)
Alt. Names/Synonyms: CDC2-associated protein CKS1; CDC28 protein kinase 1; CDC28 protein kinase 1B; CDC28 protein kinase regulatory subunit 1B; cell division control protein CKS1; CKS-1; CKS1; CKS1B; ckshs1; Cyclin-dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS-143; PNAS-16; PNAS-18
Gene Symbols: CKS1B
Molecular weight: 9,660 Da
Basal Isoelectric point: 8.89  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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