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MST3 a protein kinase of the STE20 family. Activated by caspase-mediated cleavage Note: This description may include information from UniProtKB.
Protein type: EC; Kinase, protein; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; YSK subfamily
Chromosomal Location of Human Ortholog: 13q32.2
Cellular Component: cytoplasm; cytosol; Golgi apparatus; nucleolus; nucleoplasm; nucleus
Molecular Function: cadherin binding; MAP kinase kinase kinase kinase activity; protein binding; protein kinase activity; protein serine/threonine kinase activity
Biological Process: cellular response to starvation; induction of apoptosis by oxidative stress; negative regulation of cell migration; neurite morphogenesis; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of apoptosis; regulation of axon regeneration; regulation of mitotic cell cycle; response to hydrogen peroxide; signal transduction; stress-activated protein kinase signaling pathway
Reference #:  Q9Y6E0 (UniProtKB)
Alt. Names/Synonyms: Mammalian STE20-like protein kinase 3; MST-3; MST3; MST3B; serine/threonine kinase 24 (STE20 homolog, yeast); Serine/threonine-protein kinase 24; STE20; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK24; STK3
Gene Symbols: STK24
Molecular weight: 49,308 Da
Basal Isoelectric point: 5.49  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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