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RhoE Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Binds ROCK1. Interacts with UBXD5. Ubiquitous. Belongs to the small GTPase superfamily. Rho family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q23.3
Cellular Component: focal adhesion
Molecular Function: protein binding
Biological Process: actin cytoskeleton organization and biogenesis; cell adhesion
Reference #:  P61587 (UniProtKB)
Alt. Names/Synonyms: ARHE; memB; Protein MemB; ras homolog gene family, member E; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; RHO8; RHOE; RND3; small GTP binding protein Rho8
Gene Symbols: RND3
Molecular weight: 27,368 Da
Basal Isoelectric point: 8.78  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics  |  Microtubule Dynamics
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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