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GM130 Golgi auto-antigen; probably involved in maintaining cis-Golgi structure. Part of a larger oligomeric complex. Interacts with p115. Interacts with RAB1B that has been activated by GTP-binding. Interacts with GORASP1/GRASP65 and ZFPL1. Belongs to the GOLGA2 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component: cis-Golgi network; ER to Golgi transport vesicle; ER-Golgi intermediate compartment membrane; Golgi apparatus; Golgi cis cisterna; Golgi membrane; nucleus; spindle pole
Molecular Function: cadherin binding; microtubule binding; protein binding; protein kinase binding; syntaxin binding
Biological Process: asymmetric cell division; centrosome cycle; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; microtubule nucleation; negative regulation of autophagy; negative regulation of protein binding; positive regulation of protein amino acid glycosylation; protein amino acid glycosylation; protein homotetramerization; spindle assembly
Reference #:  Q08379 (UniProtKB)
Alt. Names/Synonyms: 130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; GOGA2; GOLGA2; golgi autoantigen, golgin subfamily a, 2; Golgi matrix protein GM130; golgin A2; Golgin subfamily A member 2; Golgin-95; MGC20672; SY11 protein
Gene Symbols: GOLGA2
Molecular weight: 113,086 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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