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Protein Page:

RASGRP3 Guanine nucleotide exchange factor (GEF) for Ras and Rap1. Belongs to the RASGRP family. Note: This description may include information from UniProtKB.
Protein type: GEF; GEF, Ras
Chromosomal Location of Human Ortholog: 2p22.3
Cellular Component: plasma membrane
Molecular Function: GTPase activator activity; guanyl-nucleotide exchange factor activity; protein binding; Ras guanyl-nucleotide exchange factor activity; signal transducer activity
Biological Process: MAPKKK cascade; small GTPase mediated signal transduction
Reference #:  Q8IV61 (UniProtKB)
Alt. Names/Synonyms: Calcium and DAG-regulated guanine nucleotide exchange factor III; GRP3; Guanine nucleotide exchange factor for Rap1; KIAA0846; RAS guanyl releasing protein 3 (calcium and DAG-regulated); Ras guanyl-releasing protein 3; RASGRP3
Gene Symbols: RASGRP3
Molecular weight: 78,332 Da
Basal Isoelectric point: 6.33  Predict pI for various phosphorylation states
CST Pathways:  B Cell Receptor Signaling  |  GPCR Signaling to MAPKs
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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