Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Interacts with MYLK. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Alt. Names/Synonyms: AGTPBP1; ATP/GTP binding protein 1; ATP/GTP-binding protein 1; CBPC1; CCP1; Cytosolic carboxypeptidase 1; DKFZp686M20191; KIAA1035; Nervous system nuclear protein induced by axotomy; NNA1