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PROTOR2 May be part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization. Belongs to the PROTOR family. May replace PROTOR1 in the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 11p13-p12
Cellular Component: TORC2 complex
Molecular Function: protein binding; ubiquitin protein ligase binding
Biological Process: negative regulation of protein amino acid phosphorylation
Reference #:  Q6MZQ0 (UniProtKB)
Alt. Names/Synonyms: FLJ14213; FLJ22630; MGC16218; proline rich 5 like; Protein observed with Rictor-2; Protor-2; PROTOR2; PRR5L
Gene Symbols: PRR5L
Molecular weight: 40,836 Da
Basal Isoelectric point: 6.28  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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