Nup98 and Nup96 play a role in the bidirectional transport across the nucleoporin complex (NPC). The repeat domain in Nup98 has a direct role in the transport. Nup98 interacts directly with Nup96. Nup96 is part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus. May interact with RAE1. Interacts with vesicular stomatitis virus protein M. Belongs to the nucleoporin GLFG family. 6 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Nucleoporin
Biological Process: DNA replication; mitotic nuclear envelope disassembly; mRNA export from nucleus; nuclear pore complex assembly; nuclear pore organization and biogenesis; nucleocytoplasmic transport; positive regulation of mRNA splicing, via spliceosome; positive regulation of transcription from RNA polymerase II promoter; protein import into nucleus; protein sumoylation; proteolysis; regulation of glycolysis; RNA export from nucleus; sister chromatid cohesion; tRNA export from nucleus; viral process; viral transcription