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SGTA Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. Homooligomerize. Interacts with NS1 from parvovirus H-1, with Vpu and Gag from HIV-1. Interacts with SARS- CoV accessory protein 7a. Interacts with DNAJC5 and DNAJC5B. Ubiquitous. Belongs to the SGT family. Note: This description may include information from UniProtKB.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cytoplasm; cytosol; membrane; nucleus
Molecular Function: protein binding; protein self-association
Biological Process: ER-associated protein catabolic process
Reference #:  O43765 (UniProtKB)
Alt. Names/Synonyms: Alpha-SGT; alphaSGT; hSGT; protein containing three tetratricopeptide repeats; SGT; SGT1; SGTA; small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; Small glutamine-rich tetratricopeptide repeat-containing protein alpha; UBP; Vpu-binding protein
Gene Symbols: SGTA
Molecular weight: 34,063 Da
Basal Isoelectric point: 4.81  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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