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GFAT2 Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Highest levels of expression in heart, placenta, and spinal cord. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC; Transferase
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component: cytosol
Molecular Function: glutamine-fructose-6-phosphate transaminase (isomerizing) activity; protein binding
Biological Process: energy reserve metabolic process; fructose 6-phosphate metabolic process; protein amino acid N-linked glycosylation; UDP-N-acetylglucosamine biosynthetic process; UDP-N-acetylglucosamine metabolic process
Reference #:  O94808 (UniProtKB)
Alt. Names/Synonyms: D-fructose-6-phosphate amidotransferase 2; FLJ10380; GFAT 2; GFAT2; GFPT2; Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2; glutamine-fructose-6-phosphate transaminase 2; glutamine: fructose-6-phosphate aminotransferase 2; Glutamine:fructose 6 phosphate amidotransferase 2; Hexosephosphate aminotransferase 2
Gene Symbols: GFPT2
Molecular weight: 76,931 Da
Basal Isoelectric point: 7.03  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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