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Protein Page:

GPNMB Could be a melanogenic enzyme. Belongs to the PMEL/NMB family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 7p15.3
Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: heparin binding; integrin binding; protein binding; receptor agonist activity; syndecan binding
Biological Process: cell-cell signaling; negative regulation of cell proliferation; negative regulation of cytokine production; negative regulation of T cell activation; negative regulation of T cell proliferation; positive regulation of cell migration; positive regulation of protein amino acid autophosphorylation; positive regulation of protein amino acid phosphorylation; regulation of tissue remodeling; signal transduction
Reference #:  Q14956 (UniProtKB)
Alt. Names/Synonyms: glycoprotein (transmembrane) nmb; glycoprotein NMB; glycoprotein nmb-like protein; GPNMB; HGFIN; NMB; osteoactivin; Transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB
Gene Symbols: GPNMB
Molecular weight: 63,923 Da
Basal Isoelectric point: 6.17  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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