Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. Homodimer. Belongs to the DNA/RNA non-specific endonuclease family. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Deoxyribonuclease; EC 3.1.30.-; Mitochondrial; Ribonuclease