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S100A6 May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. Belongs to the S-100 family. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membrane; nuclear envelope; nucleus; perinuclear region of cytoplasm; ruffle
Molecular Function: calcium ion binding; calcium-dependent protein binding; protein binding; protein homodimerization activity; tropomyosin binding
Biological Process: signal transduction
Reference #:  P06703 (UniProtKB)
Alt. Names/Synonyms: 2A9; 5B10; CABP; CACY; Calcyclin; Growth factor-inducible protein 2A9; MLN 4; PRA; Prolactin receptor-associated protein; Protein S100-A6; S100 calcium binding protein A6; S100 calcium-binding protein A6; S100 calcium-binding protein A6 (calcyclin); S100A6; S10A6
Gene Symbols: S100A6
Molecular weight: 10,180 Da
Basal Isoelectric point: 5.32  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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